2025

• Guzmán, N., & Letelier, P. (2025). Development of a Model for Predicting Mortality Among Patients Hospitalized with COVID-19 During Their Stay in a Clinical Centre. Journal of Clinical Medicine, 13(23), 7300. https://doi.org/10.3390/jcm13237300

• Hernández-Monsalves, A. H., Letelier, P., Morales, C., Rojas, E., Saez, M. A., Coña, N., Díaz, J., San Martín, A., Garcés, P., Espinal-Enriquez, J., & Guzmán, N. (2025). A Machine Learning Model for Predicting Intensive Care Unit Admission in Inpatients with COVID-19 Using Clinical Data and Laboratory Biomarkers. Biomedicines, 13(5), 1025. https://doi.org/10.3390/biomedicines13051025

• Herrera-Bravo, J., Arancibia-Diaz, A., Letelier, P., Sandoval, C., Mora-Lagos, B., Herrera, L., Cottet, L., Setzer, W. N., Calina, D., & Sharifi-Rad, J. (2025). Natural modulators of Wnt/β-catenin signaling in cancer: current evidence and emerging therapeutic insights. MedComm. (En prensa / Aceptado).

• Letelier, P., Arroyo, N., Monsalves, D., Chicahual, C., Boguen, R., & Guzmán, N. (2025). REFERENCE INTERVALS OF HEMATOLOGICAL PARAMETERS IN THE CHILEAN ADULT POPULATION AND THE MAPUCHE ETHNIC GROUP. Annals of Laboratory Medicine / Advances in Laboratory Medicine, 6(1), 59-68. https://doi.org/10.1515/almed-2024-0080

• Letelier, P., Fierro, G. F., Cuminao, K. A., Huenchuleo, A. B., Boguen, R. E., & Guzmán, N. H. (2025). Evaluación de la precisión de un medidor portátil de glucosa en sangre en comparación con métodos de referencia. Journal of Clinical Medicine. (Manuscrito enviado).

• Letelier, P., Pozo, K., Saavedra, N., Garcés, M., Salazar, L., Rojas, G., Burgos, V., & Guzmán, N. (2025). Identification of polycyclic aromatic hydrocarbons (PAHs) obtained by passive sampling and their in vitro effect on human pulmonary epithelial cell lines. Journal of Environmental Science and Health, Part A. (Manuscrito enviado).

• Rivera, B., Aroca, C., González, B., Guzmán, N., Letelier, P., Uribe, P., Fornés, M., Villegas, J. V., & Boguen, R. (2025). Bacteria-Mediated Anomalous Rho GTPase Activation Alters Sperm Structure and Provokes Premature Capacitation Events: A Possible Mechanism of Infertility. International Journal of Molecular Sciences, 26(8), 3783. https://doi.org/10.3390/ijms26083783

• Rojas, E., Cartas-Espinel, I., Álvarez, P., Moris, M., Salazar, M., Boguen, R., Letelier, P., San Martín, L., San Martín, V., Morales, C., & Guzmán, N. (2025). Computer Viewing Model for classification of erythrocytes infected with Plasmodium spp. applied to Malaria Diagnosis using optical microscope. Medicina, 61. https://doi.org/10.3390/medicina61070940

2024

• Letelier, P., Delgado, H., Garrido, F., Quiñones, F., San Martín, A., Hernández, L., Garcés, P., Guzmán-Oyarzo, D., Boguen, R., Hernandez, A., Medina, G., Schwerter, P., & Guzmán, N. (2024). Dynamic changes of hematological and hemostatic parameters in COVID-19 hospitalized patients: Potential role as severity biomarkers for the Chilean population. Journal of Medical Biochemistry, 43(1), 1-9. https://doi.org/10.5937/jomb0-47588

2023

• Andaur, M., Sobarzo, V., Toro, Y., Chacón, N., Aravena, Y., Fernández, H., Rogel, R., Escandón-Nagel, N., Huircapán, P., Medina, G., Letelier, P., Leyan, P., Boguen, R., Hernández, A., & Guzmán, N. (2023). Conocimiento y conductas de riesgo de VIH/SIDA en adolescentes chilenos pertenecientes a colegios urbano y rural: ¿Es necesario enfocar la promoción y prevención de la enfermedad con pertinencia territorial? Revista Médica de Chile, 151(4), 410-428. https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872023000400428

• Letelier, P., Acuña, R., Garrido, I., López, J., Sanhueza, G., Seguel, C., Riquelme, I., Guzmán, N., & Hernández, A. H. (2023). Reference intervals of biochemical parameters in Chilean adults. Journal of Medical Biochemistry, 42(1), 1–11. https://doi.org/10.5937/jomb0-37704

• Letelier, P., Saldías, R., Loren, P., Riquelme, I., & Guzmán, N. (2023). MicroRNAs as potential biomarkers of environmental exposure to Polycyclic Aromatic Hydrocarbons and their link with inflammation and lung cancer. International Journal of Molecular Sciences, 24(23), 16984. https://doi.org/10.3390/ijms242316984

• Tosta Pérez, M., Herrera Belén, L., Letelier, P., Calle, Y., Pessoa Junior, Adalberto., & Farías, J. G. (2023). L-asparaginase as the gold standard in the treatment of acute lymphoblastic leukemia: a comprehensive review. Medical Oncology, 40, 163. https://doi.org/10.1007/s12032-023-02014-9

• Viscardi, S., Marileo, L., Delgado, H. A., San Martin, A., Hernández, L., Garcés, P., Guzmán-Oyarzo, D., Boguen, R., Medina, G., Letelier, P., Villano, I., & Guzmán, N. (2023). Obesity is associated with changes in laboratory biomarkers in chilean patients hospitalized for COVID-19. Journal of Clinical Medicine, 12(10), 3392. https://doi.org/10.3390/jcm12103392

2022

• Aburto, S., Cisterna, M., Acuña, J., Ruíz, C., Viscardi, S., Márquez, J. L., Villano, I., Letelier, P., & Guzmán, N. (2022). Obesity as a risk factor for severe COVID-19 in hospitalized patients: Epidemiology and potential mechanisms. Healthcare, 10(10), 1838. https://doi.org/10.3390/healthcare10101838

• Medina, G., Andaur Rademacher, M., Letelier Arias, P., Leyan Bravo, P., Guzman, N., Hernández, A., Boguen, R., Pereira, W. A., Figueroa Villalobos, E., & Fernández, H. (2022). Long-term survive of Aliarcobacter butzleri in two models symbiotic interaction with Acanthamoeba castellanii. Archives of Microbiology, 204, 610. https://doi.org/10.1007/s00203-022-03223-1

2021

• Letelier, P., Encina, N., Morales, P., Riffo, A., Silva, H., Riquelme, I., & Guzmán, N. (2021). Role of biochemical markers in the monitoring of COVID-19 patients. Journal of Medical Biochemistry, 40(2), 115-128. https://doi.org/10.5937/jomb0-29341

• Letelier, P., Guzmán, N., Medina, G., Calcumil, L., Huencho, P., Mora, J., Quiñones, F., Jara, J., Reyno, C., Farías, J. G., Herrera, L., Brebi, P., Riquelme, I., & San Martín, A. (2021). Workflow Optimization in a Clinical Laboratory using Lean management principles in the pre-analytical phase. Journal of Medical Biochemistry, 40(1), 1–7. https://doi.org/10.5937/jomb0-25656

• Riquelme, I., Pérez-Moreno, P., Letelier, P., Brebi, P., & Roa, J. C. (2021). The emerging role of PIWI-interacting RNAs (piRNAs) in gastrointestinal cancers: an updated perspective. Cancers, 14(1), 221. https://doi.org/10.3390/cancers14010221

2020

• Guzmán, N., Vega, M., Reyes, F., Guzmán, D., Andaur, M., Boguen, R., & Letelier, P. (2020). Farmacogenómica de los anticoagulantes orales: la importancia de establecer algoritmos de dosificación en población chilena. Revista Médica de Chile, 148(9), 1307-1314. https://doi.org/10.4067/S0034-98872020000901307

• Reyes, M. E., Riquelme, I., Salvo, T., Zanella, L., Letelier, P., & Brebi, P. (2020). Brown Seaweed Fucoidan in Cancer: Implications in Metastasis and Drug Resistance. Marine Drugs, 18(5), 232. https://doi.org/10.3390/md18050232